Opportunity Information: Apply for CDC RFA EH17 1703

The grant opportunity titled "Increasing Newborn Screening Laboratory Capability to Detect Severe Combined Immunodeficiency (SCID) Using Next Generation Sequencing Technologies" is a Centers for Disease Control and Prevention (CDC) cooperative agreement designed to expand and strengthen newborn screening laboratory capacity in the United States and its territories. Its central aim is to increase the number of state and territorial public health laboratories that can screen newborns for SCID and related primary immunodeficiencies using next generation sequencing (NGS) methods. In practical terms, the opportunity is focused on helping public health newborn screening systems move beyond traditional screening approaches and build the technical and operational capability to use modern genomic technologies to improve detection and follow-up for these serious immune disorders.

This funding was released by the CDC under the National Center for Environmental Health (NCEH) and is listed as a discretionary opportunity using a cooperative agreement funding instrument, meaning recipients would typically work in closer coordination with the CDC than under a standard grant. The funding activity category is health, and the opportunity is associated with CFDA number 93.065. The funding opportunity number is CDC RFA EH17 1703, with an original application closing date of May 31, 2017. The program anticipated making about four awards, with an award ceiling of $150,000 per award, indicating relatively targeted, capacity-building projects rather than large-scale statewide program expansions.

Eligibility is described as unrestricted in the source data, but the narrative requirements make the intended applicant pool more specific. Awards are authorized for states, political subdivisions, and other public and nonprofit private entities, but applicants must be directly tied to an established state or territorial newborn screening program. Specifically, the applicant must represent, or serve as an administrative partner to, a newborn screening program in a US state or territory that already screens for SCID. To document this, applicants are expected to submit a letter certifying that they represent or are an administrative partner to an established state or territorial newborn screening program. This requirement signals that the CDC is prioritizing applicants who are already embedded in operational newborn screening systems and can realistically implement or enhance NGS-based approaches within an existing public health framework.

Overall, the opportunity is best understood as an effort to modernize and broaden newborn screening laboratory capabilities for SCID and other primary immunodeficiencies by supporting the adoption or enhancement of NGS technologies in public health settings. The emphasis on established programs already screening for SCID suggests the program is intended to accelerate advanced molecular capability in jurisdictions with baseline SCID screening in place, potentially improving confirmatory testing workflows, variant detection, and the capacity to identify immunodeficiency conditions that may not be fully captured through older methods alone.

  • The Centers for Disease Control - NCEH in the health sector is offering a public funding opportunity titled "Increasing Newborn Screening Laboratory Capability to Detect Severe Combined Immunodeficiency (SCID) Using Next Generation Sequencing Technologies" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.065.
  • This funding opportunity was created on 2017-03-31.
  • Applicants must submit their applications by 2017-05-31. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $150,000.00 in funding.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted.
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