Opportunity Information: Apply for RFA HD 25 010
The Road to Prevention of Stillbirth: Clinical Research Centers (UG1 Clinical Trial Optional) (RFA-HD-25-010) is a National Institutes of Health (NIH) funding opportunity that will build a coordinated, multi-site Stillbirth Research Consortium in the United States. Through this NOFO, NIH is seeking applications from organizations that can serve as Research Centers (RCs) within that consortium. These RCs will work in close partnership with a separately competed Data Coordinating Center (DCC) that is being solicited under a parallel announcement (RFA-HD-25-011). Taken together, the RCs and the DCC are intended to function as an integrated network that can design, conduct, and synthesize cutting-edge stillbirth research across basic science, translational science, clinical research, and data science.
A central theme of the opportunity is prevention-focused impact, with a strong expectation that funded sites will apply an equity lens to stillbirth research. In practical terms, the consortium is meant to generate knowledge that can reduce stillbirth incidence overall while explicitly addressing disproportionate burdens in vulnerable and historically underserved populations. This emphasis signals that applicants should be prepared to study drivers of disparities, improve the representativeness of enrolled populations, and develop approaches that are responsive to community and clinical realities where stillbirth risk is highest. The scope is intentionally broad (basic, translational, clinical, and/or data sciences), allowing Research Centers to propose complementary strengths that, when combined across the network, accelerate discovery and translation into prevention strategies.
The award mechanism is a UG1 cooperative agreement, which generally means NIH will have substantial programmatic involvement compared to a traditional research project grant. Applicants should anticipate a collaborative governance style where funded RCs coordinate with NIH and with one another, align on common protocols or shared measures when appropriate, and contribute to consortium-wide goals. The “Clinical Trial Optional” designation indicates that proposed activities may include clinical trials, but a trial is not required; applicants can propose observational studies, mechanistic investigations, translational work, or data-driven research, as long as the plan fits the consortium’s prevention and equity priorities and can operate effectively in a multi-center environment supported by a DCC.
Eligibility is broad and spans many organization types that could credibly support a clinical research center or research hub. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education and private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits (with or without 501(c)(3) status) other than institutions of higher education; for-profit organizations (other than small businesses); small businesses; and other entities. The NOFO also explicitly calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and eligible federal agencies. In terms of international involvement, non-U.S. (foreign) organizations are not eligible to apply as applicants; however, non-U.S. components of U.S. organizations are eligible, and foreign components are allowed as defined in the NIH Grants Policy Statement. U.S. territories or possessions are also included among eligible applicants.
From an administrative standpoint, the opportunity is categorized as discretionary funding and uses the cooperative agreement funding instrument, with an activity category listed as Health, Income Security and Social Services and CFDA number 93.865. The original application due date listed is 2024-11-01, and the opportunity was created on 2024-07-19. While the provided excerpt does not specify an award ceiling or the expected number of awards, the overall structure implies multiple Research Centers will be funded to form a network alongside a single DCC, with the consortium’s success depending on coordinated, multi-site participation rather than isolated single-institution projects.
In summary, this NOFO is designed to assemble a national, collaborative research infrastructure focused on preventing stillbirth, generating new scientific knowledge across multiple research domains, and directly confronting inequities in stillbirth outcomes. Competitive applicants will be those that can function as strong consortium partners, bring clear scientific and operational strengths to stillbirth research, and demonstrate credible plans to incorporate equity-driven approaches that can lead to measurable reductions in stillbirth risk in vulnerable populations.Apply for RFA HD 25 010
- The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "The Road to Prevention of Stillbirth Clinical Research Centers (UG1 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
- This funding opportunity was created on 2024-07-19.
- Applicants must submit their applications by 2024-11-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Collaborative Research in Genomics, Epigenomics, and Bioinformatics in Gynecologic Health and Disease (R21) Apply for RFA HD 16 004 Funding Number: RFA HD 16 004 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
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| NICHD Small Research Grant Program (R03 Clinical Trial Required) Apply for PA 25 125 Funding Number: PA 25 125 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
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| Advancing Research Careers (ARC) Predoctoral to Postdoctoral Transition Award to Promote Diversity (F99/K00 - Clinical Trial Not Allowed) Apply for PAR 25 084 Funding Number: PAR 25 084 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Archiving and Documenting Child Health and Human Development Data Sets (R03 Clinical Trial Not Allowed) Apply for PAR 25 092 Funding Number: PAR 25 092 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
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